APNEA Inhibitor

Name: APNEA Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5753546
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753546

APNEA (N6-[2-(4-Aminophenyl)ethyl]adenosine) is a potent and non-selective agonist of A3 adenosine receptor. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

APNEA, Inhibitor

Full Product Name

APNEA

Product Gene Name

APNEA, inhibitor

Product Synonym Names

N6-[2-(4-Aminophenyl)ethyl]adenosine

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

386.41

Solubility

DMSO: 50mg/mL (129.40mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C18H22N6O4

SMILES

OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C2N=CN=C3NCCC4=CC=C(N)C=C4)O1)O)O

CAS Number

89705-21-5

Target & IC50

Adenosine receptor

In Vitro

APNEA (N6-[2-(4-Aminophenyl)ethyl]adenosine) is a non-selective the adenosine A3 receptors agonist, APNEA (0.0039-1mg/kg) enhances the protective activity of carbamazepine. APNEA at low doses potentiates the protective activity of Carbamazepine most likely through the A subtype of adenosine receptors. At higher doses, APNEA seems to enhance the anticonvulsive effect of other antiepileptics via adenosine A1 receptors[1].

Product Categories/Family for APNEA, inhibitor

Neuroscience; AChR

Product References and Citations for APNEA, inhibitor

Borowicz KK, et al. N6-2-(4-aminophenyl)ethyl-adenosine enhances the anticonvulsive activity of antiepileptic drugs. Eur J Pharmacol. 1997 May 30;327(2-3):125-133.
Borowicz KK, et al. N6-2-(4-aminophenyl)ethyl-adenosine enhances the anticonvulsive activity of antiepileptic drugs. Eur J Pharmacol. 1997 May 30;327(2-3):125-133.
Borowicz KK, et al. N(6)-2-(4-aminophenyl)ethyl-adenosine enhances the anticonvulsive action of conventional antiepileptic drugs in the kindling model of epilepsy in rats. Eur Neuropsychopharmacol. 2000 Jul;10(4):237-243.
Borowicz KK, et al. N(6)-2-(4-aminophenyl)ethyl-adenosine enhances the anticonvulsive action of conventional antiepileptic drugs in the kindling model of epilepsy in rats. Eur Neuropsychopharmacol. 2000 Jul;10(4):237-243.

Other Notes

Small volumes of APNEA, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for APNEA purchase

MBS5753546 is an inhibitor targeting APNEA.