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Naloxone benzoylhydrazone Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753551

Naloxone benzoylhydrazone is a prototypic kappa3-opioid receptor agonist, and a partial agonist at the cloned u and delta opioid receptors, and an antagonist at opioid-like NOP receptors, has potently analgesia effect. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Naloxone benzoylhydrazone, Inhibitor
Full Product Name
Naloxone benzoylhydrazone
Product Synonym Names
NalBzoH
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
445.51
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C26H27N3O4
SMILES
O[C@]12[C@@]34C5=C(C(O)=CC=C5C[C@@]2([H])N(CC=C)CC4)O[C@@]3([H])/C(CC1)=N/NC(C6=CC=CC=C6)=O
CAS Number
119630-94-3
Target & IC50
kappa3-opioid receptor

Product References and Citations for Naloxone benzoylhydrazone, inhibitor

Olianas MC, et al. Agonist activity of naloxone benzoylhydrazone at recombinant and native opioid receptors. Br J Pharmacol. 2006 Feb;147(4):360-70.
Olianas MC, et al. Agonist activity of naloxone benzoylhydrazone at recombinant and native opioid receptors. Br J Pharmacol. 2006 Feb;147(4):360-70.
Connor M, et al. Has the sun set on kappa3-opioid receptors. Br J Pharmacol. 2006 Feb;147(4):349-50.
Connor M, et al. Has the sun set on kappa3-opioid receptors. Br J Pharmacol. 2006 Feb;147(4):349-50.
Paul D, et al. Naloxone benzoylhydrazone (NalBzoH) analgesia. J Pharmacol Exp Ther. 1990 Nov;255(2):769-74.
Paul D, et al. Naloxone benzoylhydrazone (NalBzoH) analgesia. J Pharmacol Exp Ther. 1990 Nov;255(2):769-74.
Gistrak MA, et al. Pharmacological actions of a novel mixed opiate agonist/antagonist: naloxone benzoylhydrazone. J Pharmacol Exp Ther. 1989 Nov;251(2):469-76.
Gistrak MA, et al. Pharmacological actions of a novel mixed opiate agonist/antagonist: naloxone benzoylhydrazone. J Pharmacol Exp Ther. 1989 Nov;251(2):469-76.

Other Notes

Small volumes of Naloxone benzoylhydrazone, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS5753551 is an inhibitor targeting Naloxone benzoylhydrazone.
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