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NSC305787 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753596

MBS5753596 is an inhibitor targeting NSC305787. NSC305787 is an ezrin inhibitor(Kd of 5.85uM), with antitumor activity. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NSC305787, Inhibitor
Full Product Name
NSC305787
Product Gene Name
NSC305787, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
445.42
Solubility
DMSO: 6mg/mL (13.47mM) Need ultrasonic and warming
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C25H30Cl2N2O
SMILES
OC(C1NCCCC1)C2=CC(C3(C4)CC5CC4CC(C5)C3)=NC6=C(Cl)C=C(Cl)C=C26
CAS Number
785718-37-8
Target & IC50
ezrin: ic50 8.3uM

Structure of NSC305787, inhibitor

NSC305787 Inhibitor – Cat# MBS5753596

Product References and Citations for NSC305787, inhibitor

Bulut G, et al. Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells. Oncogene. 2012 Jan 19;31(3):269-81.
Bulut G, et al. Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells. Oncogene. 2012 Jan 19;31(3):269-81.
a‡elik H, et al. Ezrin Inhibition Up-regulates Stress Response Gene Expression. J Biol Chem. 2016 Jun 17;291(25):13257-70.
a‡elik H, et al. Ezrin Inhibition Up-regulates Stress Response Gene Expression. J Biol Chem. 2016 Jun 17;291(25):13257-70.

Other Notes

Small volumes of NSC305787, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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