ORM-10103 Inhibitor

Name: ORM-10103 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5753623
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753623

MBS5753623 is an inhibitor targeting ORM-10103. ORM-10103 is a specific the Na+/Ca2+ exchanger (NCX) inhibitor. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ORM-10103, Inhibitor

Full Product Name

ORM-10103

Product Gene Name

ORM-10103, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

348.35

Solubility

DMSO: 250mg/mL (717.67mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C20H16N2O4

SMILES

O=[N+](C1=CN=C(OC2=CC=C3C(CCC(C4=CC=CC=C4)O3)=C2)C=C1)[O-]

CAS Number

488847-28-5

Target & IC50

NCX -80mV: ic50 55
NCX 20mV: ic50 67nM

Product References and Citations for ORM-10103, inhibitor

Jost N, et al. ORM-10103, a novel specific inhibitor of the Na+/Ca2+ exchanger, decreases early and delayed afterdepolarizations in the canine heart. Br J Pharmacol. 2013 Oct;170(4):768-78.
Jost N, et al. ORM-10103, a novel specific inhibitor of the Na+/Ca2+ exchanger, decreases early and delayed afterdepolarizations in the canine heart. Br J Pharmacol. 2013 Oct;170(4):768-78.
Kohajda Z, et al. The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias In vitro and In Vivo Experiments. PLoS One. 2016 Nov 10;11(11):e0166041.
Kohajda Z, et al. The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias In vitro and In Vivo Experiments. PLoS One. 2016 Nov 10;11(11):e0166041.

Other Notes

Small volumes of ORM-10103, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

ORM-10103 Inhibitor

Product Overview

Structure of ORM-10103, inhibitor

Related Product Information for ORM-10103, inhibitor

Product References and Citations for ORM-10103, inhibitor

Other Notes