Parsaclisib Inhibitor

Name: Parsaclisib Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5753644
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753644

Parsaclisib is a potent and selective inhibitor of PI3Kdelta(IC50 of 1nM at 1mM ATP) More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Parsaclisib, Inhibitor

Full Product Name

Parsaclisib

Product Synonym Names

INCB050465

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

432.88

Solubility

DMSO: 125mg/mL (288.76mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C20H22ClFN6O2

SMILES

CCOC1=C([C@@H](C2)CNC2=O)C(F)=C(Cl)C=C1[C@@H](N3C4=NC=NC(N)=C4C(C)=N3)C

CAS Number

1426698-88-5

Target & IC50

PI3Kdelta, 1mM ATP: ic50 1nM

Product Categories/Family for Parsaclisib, inhibitor

PI3K/Akt/mTOR signaling; PI3K

Product References and Citations for Parsaclisib, inhibitor

Niu Shin, et al. Abstract 2671: INCB050465, a novel PI3Kdelta inhibitor, synergizes with PIM protein kinase inhibition to cause tumor regression in a model of DLBCL. Cancer Research. 2015, Aug. 75(15).
Niu Shin, et al. Abstract 2671: INCB050465, a novel PI3Kdelta inhibitor, synergizes with PIM protein kinase inhibition to cause tumor regression in a model of DLBCL. Cancer Research. 2015, Aug. 75(15).

Other Notes

Small volumes of Parsaclisib, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Parsaclisib purchase

MBS5753644 is an inhibitor targeting Parsaclisib.