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PI4KIIIbeta-IN-10 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753692

MBS5753692 is an inhibitor targeting PI4KIIIbeta-IN-10. PI4KIIIbeta-IN-10 is a potent inhibitor of PI4KIIIbeta (IC50 of 3.6nM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PI4KIIIbeta-IN-10, Inhibitor
Full Product Name
PI4KIIIbeta-IN-10
Product Gene Name
PI4KIIIbeta-IN-10, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
475.58
Solubility
DMSO: 30mg/mL (63.08mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C22H25N3O5S2
SMILES
COC1=CC=C(C2=C(C)N=C(NC(C(C)(C)C)=O)S2)C=C1S(NC3=CC=C(O)C=C3)(=O)=O
CAS Number
1881233-39-1
Target & IC50
PI4KIIIbeta: ic50 3.6nM
PI4KIIIalpha: ic50 3uM
PI3Kdelta: ic50 720nM
PI3KC2gamma: ic50 1uM
PI3Kalpha: ic50 10uM
PI3Kgamma: ic50 20uM

Product Categories/Family for PI4KIIIbeta-IN-10, inhibitor

PI3K/Akt/mTOR signaling; PI3K

Structure of PI4KIIIbeta-IN-10, inhibitor

PI4KIIIbeta-IN-10 Inhibitor – Cat# MBS5753692

Product References and Citations for PI4KIIIbeta-IN-10, inhibitor

Rutaganira FU, et al. Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase IIIbeta. J Med Chem. 2016 Mar 10;59(5):1830-9.
Rutaganira FU, et al. Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase IIIbeta. J Med Chem. 2016 Mar 10;59(5):1830-9.

Other Notes

Small volumes of PI4KIIIbeta-IN-10, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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