PLpro Inhibitor

Name: PLpro Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5753708
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753708

PLpro inhibitor is a potent papain-like protease (PLpro) inhibitor(IC50 of 2.6uM) More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PLpro, Inhibitor

Full Product Name

PLpro inhibitor

Product Gene Name

PLpro, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

346.42

Solubility

DMSO: 40mg/mL (115.47mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C22H22N2O2

SMILES

C[C@@H](NC(=O)c1cc(NC(C)=O)ccc1C)c1cccc2ccccc12

CAS Number

1093070-14-4

Target & IC50

papain-like protease (PLpro): ic50 2.6uM
SARS-CoV-2 PLpro: ic50 21.0uM (EC50)

Product Categories/Family for PLpro, inhibitor

Anti-infection

Product References and Citations for PLpro, inhibitor

Ratia, K., et al., A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication. Proc Natl Acad Sci U S A, 2008. 105(42): p. 16119-24.
Ratia, K., et al., A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication. Proc Natl Acad Sci U S A, 2008. 105(42): p. 16119-24.
http://www.google.com/patents/WO2010022355A1cl=en
http://www.google.com/patents/WO2010022355A1cl=en

Other Notes

Small volumes of PLpro, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLpro purchase

MBS5753708 is an inhibitor targeting PLpro. Also known as PLpro inhibitor.