PSB-12062 Inhibitor

Name: PSB-12062 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5753735
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753735

PSB-12062 is a potent and selective antagonist of P2X4(IC50 of 1.38 uM for human P2X4). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PSB-12062, Inhibitor

Full Product Name

PSB-12062

Product Gene Name

PSB-12062, inhibitor

Product Synonym Names

N-(p-Methylphenylsulfonyl)phenoxazine

Form/Format

Solid. Powder

Purity/Purification

99.97%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

337.39

Solubility

DMSO: 24mg/mL (71.13mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C19H15NO3S

SMILES

Cc1ccc(cc1)S(=O)(=O)N1c2ccccc2Oc2ccccc12

CAS Number

55476-47-6

Target & IC50

human P2X4: ic50 1.38uM
rat P2X4: ic50 92.8nM
mouse P2X4: ic50 1.76uM
P2X4

Product Categories/Family for PSB-12062, inhibitor

Neuroscience

Product References and Citations for PSB-12062, inhibitor

Hernandez-Olmos V, et al. N-substituted phenoxazine and acridone derivatives: structure-activity relationships of potent P2X4 receptor antagonists. J Med Chem. 2012 Nov 26;55(22):9576-88.
Hernandez-Olmos V, et al. N-substituted phenoxazine and acridone derivatives: structure-activity relationships of potent P2X4 receptor antagonists. J Med Chem. 2012 Nov 26;55(22):9576-88.
Stokes L, et al. P2X4 Receptor Function in the Nervous System and Current Breakthroughs in Pharmacology.Front Pharmacol. 2017 May 23;8:291.
Stokes L, et al. P2X4 Receptor Function in the Nervous System and Current Breakthroughs in Pharmacology.Front Pharmacol. 2017 May 23;8:291.

Other Notes

Small volumes of PSB-12062, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PSB-12062 purchase

MBS5753735 is an inhibitor targeting PSB-12062.