PTC596 Inhibitor

Name: PTC596 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5753742
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753742

PTC596 is an orally active and selective inhibitor of B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PTC596, Inhibitor

Full Product Name

PTC596

Product Gene Name

PTC596, inhibitor

Form/Format

Solid. Powder

Purity/Purification

100.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

420.34

Solubility

DMSO: 16.67mg/mL (39.66mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C19H13F5N6

SMILES

CC1=NC2=C(C=C(F)C=C2)N1C1=NC(N)=C(F)C(NC2=CC=C(C=C2)C(F)(F)F)=N1

CAS Number

1610964-64-1

Target & IC50

BMI-1

Product Categories/Family for PTC596, inhibitor

BMI-1; Others

Product References and Citations for PTC596, inhibitor

Nishida Y, et al. The novel BMI-1 inhibitor PTC596 downregulates MCL-1 and induces p53-independent mitochondrial apoptosis in acute myeloid leukemia progenitor cells. Blood Cancer J. 2017 Feb 17;7(2):e527.
Nishida Y, et al. The novel BMI-1 inhibitor PTC596 downregulates MCL-1 and induces p53-independent mitochondrial apoptosis in acute myeloid leukemia progenitor cells. Blood Cancer J. 2017 Feb 17;7(2):e527.
BMI1 inhibitor PTC596
BMI1 inhibitor PTC596

Other Notes

Small volumes of PTC596, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTC596 purchase

MBS5753742 is an inhibitor targeting PTC596.