QX-314 Inhibitor – Chloride

Name: QX-314 Inhibitor; Chloride; MyBioSource
Brand: MyBioSource
SKU: MBS5753758
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753758

QX-314 chloride is a membrane-impermeable permanently charged blocker of sodium channel. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

QX-314 chloride, Inhibitor

Full Product Name

QX-314 chloride

Product Gene Name

QX-314, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

298.85

Solubility

DMSO: 14.29mg/mL (47.82mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C16H27ClN2O

SMILES

O=C(NC1=C(C)C=CC=C1C)C[N+](CC)(CC)CC.[Cl-]

CAS Number

5369-03-9

Target & IC50

Sodium channel

Product Categories/Family for QX-314, inhibitor

Membrane transporter/Ion channel; Sodium Channel

Product References and Citations for QX-314, inhibitor

Rivera-Acevedo RE, et al. The quaternary lidocaine derivative, QX-314, exerts biphasic effects on transient receptor potential vanilloid subtype 1 channels in vitro. Anesthesiology. 2011 Jun;114(6):1425-34.
Rivera-Acevedo RE, et al. The quaternary lidocaine derivative, QX-314, exerts biphasic effects on transient receptor potential vanilloid subtype 1 channels in vitro. Anesthesiology. 2011 Jun;114(6):1425-34.
Talbot MJ, et al. Intracellular QX-314 inhibits calcium currents in hippocampal CA1 pyramidal neurons. J Neurophysiol. 1996 Sep;76(3):2120-4.
Talbot MJ, et al. Intracellular QX-314 inhibits calcium currents in hippocampal CA1 pyramidal neurons. J Neurophysiol. 1996 Sep;76(3):2120-4.

Other Notes

Small volumes of QX-314, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for QX-314 purchase

MBS5753758 is an inhibitor targeting QX-314. Also known as QX-314 chloride.