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(R)-Simurosertib Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753778

(R)-Simurosertib is the (R)-enantiomer of Simurosertib. Simurosertib is an orally active, selective and ATP-competitive cell division inhibitor of cycle 7 (CDC7) kinase(IC50 of More details

Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
(R)-Simurosertib, Inhibitor
Full Product Name
(R)-Simurosertib
Product Synonym Names
(R)-TAK-931
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
341.43
Solubility
DMSO: 75mg/mL (219.66mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C17H19N5OS
SMILES
O=C(C1=C(N2)C=C(C3=CNN=C3C)S1)N=C2[C@H]4CC5CCN4CC5
CAS Number
1330782-69-8
Target & IC50
Others

Product References and Citations for (R)-Simurosertib, inhibitor

K Iwai, et al. A novel CDC7-selective inhibitor TAK-931 with potent antitumor activity. European Journal of Cancer, 2016, 69 (1) :S34.
K Iwai, et al. A novel CDC7-selective inhibitor TAK-931 with potent antitumor activity. European Journal of Cancer, 2016, 69 (1) :S34.

Other Notes

Small volumes of (R)-Simurosertib, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for (R)-Simurosertib purchase

MBS5753778 is an inhibitor targeting (R)-Simurosertib.
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