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Retro-2 cycl Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753813

Retro-2 cycl is a dihydroquinazolinone (DHQZ) retrograde trafficking inhibitor. Retro-2 cycl (RN 1-001) inhibits JCPyV and HPV16 pseudovirus(IC50s of 54uM and 160uM, respectively),with antiviral agent. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Retro-2 cycl, Inhibitor
Full Product Name
Retro-2 cycl
Product Synonym Names
RN 1-001
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
320.41
Solubility
DMSO: 125mg/mL (390.13mM)
H2O: <0.1mg/mL (insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C19H16N2OS
SMILES
O=C1C2=CC=CC=C2NC(N1C3=CC=CC=C3)C4=CC=C(S4)C
CAS Number
1429192-00-6
Target & IC50
Others

Structure of Retro-2 cycl, inhibitor

Retro-2 cycl Inhibitor – Cat# MBS5753813

Product References and Citations for Retro-2 cycl, inhibitor

Carney DW, et al. Structural optimization of a retrograde trafficking inhibitor that protects cells from infections by human polyoma- and papillomaviruses. Bioorg Med Chem. 2014 Sep 1;22(17):4836-47.
Carney DW, et al. Structural optimization of a retrograde trafficking inhibitor that protects cells from infections by human polyoma- and papillomaviruses. Bioorg Med Chem. 2014 Sep 1;22(17):4836-47.

Other Notes

Small volumes of Retro-2 cycl, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Retro-2 cycl purchase

MBS5753813 is an inhibitor targeting Retro-2 cycl.
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