RHO-KINASE-IN-1 Inhibitor

Name: RHO-KINASE-IN-1 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5753820
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753820

Rho-Kinase-IN-1 is a inhibitor of Rho kinase (ROCK) with Ki values of 30.5 and 3.9nM for ROCK1 and ROCK2, respectively More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Rho-Kinase-IN-1, Inhibitor

Full Product Name

Rho-Kinase-IN-1

Product Gene Name

Rho-Kinase-IN-1, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

352.5

Solubility

DMSO: 50mg/mL (141.84mM) ultrasonic and warming and heat to 60 degree C
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C20H24N4S

SMILES

CSC1=CC=C(CN2CC(NC3=CC4=C(NN=C4)C=C3)CCC2)C=C1

CAS Number

1035094-83-7

Target & IC50

ROCK1: ic50 30.5nM (ki)
ROCK2: ic50 3.9nM (ki)

In Vitro

Rho-Kinase-IN-1 is an inhibitor of ROCK, and can be useful for treating diseases or conditions associated with excessive cell proliferation, remodeling, edema and inflammation.

Product Categories/Family for Rho-Kinase-IN-1, inhibitor

Cell Cycle/Checkpoint; ROCK; Stem Cells

Product References and Citations for Rho-Kinase-IN-1, inhibitor

Fulcher, Emilee H, et al. Method for the treatment, and prevention of the inflammatory diseases using Rho kinase inhibiting compounds. US 20090325960 A1.
Fulcher, Emilee H, et al. Method for the treatment, and prevention of the inflammatory diseases using Rho kinase inhibiting compounds. US 20090325960 A1.

Other Notes

Small volumes of Rho-Kinase-IN-1, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Rho-Kinase-IN-1 purchase

MBS5753820 is an inhibitor targeting Rho-Kinase-IN-1.