RTC-5 Inhibitor

Name: RTC-5 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5753841
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753841

RTC-5 demonstrated efficacy against a xenograft model of an EGFR driven cancer without the neurotropic effects exhibited by the parent molecules. Its effects were attributed to concomitant negative regulation of PI3K-AKT and RAS-ERK signaling More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RTC-5, Inhibitor

Full Product Name

RTC-5

Product Gene Name

RTC-5, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

510.96

Solubility

DMSO: 15mg/mL (29.36mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C24H22ClF3N2O3S

SMILES

O=S(C1=CC=C(OC(F)(F)F)C=C1)(NCCCN2C3=CC(Cl)=CC=C3CCC4=CC=CC=C42)=O

CAS Number

1423077-49-9

Target & IC50

EGFR

Product Categories/Family for RTC-5, inhibitor

Angiogenesis; EGFR; JAK/STAT signaling; Tyrosine Kinase/Adaptors

Product References and Citations for RTC-5, inhibitor

Kastrinsky DB, et al. Reengineered tricyclic anti-cancer agents. Bioorg Med Chem. 2015 Oct 1;23(19):6528-34.

Other Notes

Small volumes of RTC-5, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RTC-5 purchase

MBS5753841 is an inhibitor targeting RTC-5.