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RWJ50271 Inhibitor – RWJ 50271

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753844

RWJ 50271 is a selective lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction inhibitor(IC50 of 5.0uM in HL60 cells). More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RWJ 50271 (RWJ50271), Inhibitor
Full Product Name
RWJ 50271
Product Gene Name
Form/Format
Solid. Powder
Purity/Purification
99.22%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
410.41
Solubility
DMSO: 230mg/mL (487.32mM)) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C18H17F3N4O2S
SMILES
Cc1c(cnn1-c1nc(cs1)-c1cccc(c1)C(F)(F)F)C(=O)NCCCO
CAS Number
162112-37-0
Target & IC50
LFA-1/ICAM-1, HL60 cells: ic50 5.0uM

Structure of RWJ50271, inhibitor

RWJ50271 Inhibitor – Cat# MBS5753844

Product References and Citations for RWJ50271, inhibitor

Sanfilippo PJ, et al. Novel thiazole based heterocycles as inhibitors of LFA-1/ICAM-1 mediated cell adhesion. J Med Chem. 1995 Mar 31;38(7):1057-9.

Other Notes

Small volumes of RWJ50271, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RWJ50271 purchase

MBS5753844 is an inhibitor targeting RWJ50271. Also known as RWJ 50271.
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