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Dilmapimod Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753876

Dilmapimod is a potent inhibitor of p38 MAPK,it potentially suppresses inflammation in chronic obstructive pulmonary disease. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Dilmapimod, Inhibitor
Full Product Name
Dilmapimod
Product Synonym Names
SB-681323; GW 681323
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
456.42
Solubility
DMSO: 125mg/mL (273.87mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C23H19F3N4O3
SMILES
O=C1C=CC2=C(C3=CC=C(F)C=C3C)N=C(NC(CO)CO)N=C2N1C4=C(F)C=CC=C4F
CAS Number
444606-18-2
Target & IC50
Others
In Vitro
p38 MAPK signaling potently inhibited by Dilmapimod, measured by inhibition of sorbitol-induced pHSP27 expression.

Structure of Dilmapimod, inhibitor

Dilmapimod Inhibitor – Cat# MBS5753876

Product References and Citations for Dilmapimod, inhibitor

Singh D, et al. A randomized, placebo-controlled study of the effects of the p38 MAPK inhibitor SB-681323 on blood biomarkers of inflammation in COPD patients. J Clin Pharmacol. 2010 Jan;50(1):94-100.

Other Notes

Small volumes of Dilmapimod, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Dilmapimod purchase

MBS5753876 is an inhibitor targeting Dilmapimod.
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