SBFI-26 Inhibitor

Name: SBFI-26 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5753878
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753878

SBFI-26 is a selective and competitive fatty acid binding proteins FABP5 and FABP7 inhibitor(FABP5 and FABP7 with Kis of 0.9uM and 0.4uM, respectively), with anti-nociceptive and anti-inflammatory effects. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

SBFI-26, Inhibitor

Full Product Name

SBFI-26

Product Gene Name

SBFI-26, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

422.47

Solubility

DMSO: 100mg/mL (236.70mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C28H22O4

SMILES

O=C([C@H]1[C@@H](C2=CC=CC=C2)[C@H](C(O)=O)[C@@H]1C3=CC=CC=C3)OC4=CC=CC5=C4C=CC=C5.[Relative stereochemistry]

CAS Number

1541207-06-0

Target & IC50

FABP5: ic50 0.9uM (ki)
FABP7: ic50 0.4uM (ki)

In Vitro

carrageenan-induced thermal hyperalgesia and paw edema significantly reduced by SBFI-26 (20mg/kg, i.p.)[2]. SBFI-26 produces anti-inflammatory and antinociceptive effects in mice[2].

Product Categories/Family for SBFI-26, inhibitor

Metabolism; FABP

Product References and Citations for SBFI-26, inhibitor

Berger WT, et al. Targeting fatty acid binding protein (FABP) anandamide transporters - a novel strategy for development of anti-inflammatory and anti-nociceptive drugs. PLoS One. 2012;7(12):e50968.
Berger WT, et al. Targeting fatty acid binding protein (FABP) anandamide transporters - a novel strategy for development of anti-inflammatory and anti-nociceptive drugs. PLoS One. 2012;7(12):e50968.
Hsu HC, et al. The Antinociceptive Agent SBFI-26 Binds to Anandamide Transporters FABP5 and FABP7 at Two Different Sites. Biochemistry.2017 Jul 11;56(27):3454-3462.
Hsu HC, et al. The Antinociceptive Agent SBFI-26 Binds to Anandamide Transporters FABP5 and FABP7 at Two Different Sites. Biochemistry.2017 Jul 11;56(27):3454-3462.

Other Notes

Small volumes of SBFI-26, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SBFI-26 purchase

MBS5753878 is an inhibitor targeting SBFI-26.