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Seco-Duocarmycin TM Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753891

Seco-Duocarmycin TM is an agent of DNA alkylator belonging to Duocarmycins family that inhibits DNA synthesis. It used as the cytotoxic component in antibody-drug conjugates (ADC). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Seco-Duocarmycin TM, Inhibitor
Full Product Name
Seco-Duocarmycin TM
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
448.47
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C25H24N2O6
SMILES
OC[C@H]1C2=C(C=CC=C3)C3=C(O)C=C2N(C(C4=CC(C=C(OC)C(OC)=C5OC)=C5N4)=O)C1
CAS Number
236102-87-7
Target & IC50
Duocarmycins

Product References and Citations for Seco-Duocarmycin TM, inhibitor

Gieseg MA, et al. Comparison of the patterns of DNA alkylation by phenol and amino seco-CBI-TMI compounds: use of a PCR method for the facile preparation of single end-labelled double-stranded DNA. Anticancer Drug Des. 1999 Feb;14(1):77-84.

Other Notes

Small volumes of Seco-Duocarmycin TM, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Seco-Duocarmycin TM purchase

MBS5753891 is an inhibitor targeting Seco-Duocarmycin TM.
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