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SGN-2FF Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753903

SGN-2FF is an oral fucosylation inhibitor and inhibits fucosyltransferase activity, and has antitumor activity. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SGN-2FF, Inhibitor
Full Product Name
SGN-2FF
Product Gene Name
SGN-2FF, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
166.15
Solubility
H2O: 36.67mg/mL (220.70mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C6H11FO4
SMILES
F[C@H]1[C@@H]([C@@H]([C@H](C)OC1O)O)O
CAS Number
2089647-47-0
Target & IC50
Fucosyltransferase
In Vitro
In multiple mouse tumor models,SGN-2FF exhibits antitumor activity. SGN-2FF showing substantial tumor growth delay. SGN-2FF elevates the protective effect of a lymphoma vaccine in a syngeneic mouse model.

Structure of SGN-2FF, inhibitor

SGN-2FF Inhibitor – Cat# MBS5753903

Product References and Citations for SGN-2FF, inhibitor

Stephen C. Alley, et al. Abstract DDT02-02: SGN-2FF: A novel small molecule inhibitor of fucosylation with preclinical antitumor activity through multiple immune mechanisms. Cancer Res 2017;77(13 Suppl).

Other Notes

Small volumes of SGN-2FF, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SGN-2FF purchase

MBS5753903 is an inhibitor targeting SGN-2FF.
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