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(-)-SHIN1 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753905

MBS5753905 is an inhibitor targeting (-)-SHIN1. (-)-SHIN1 ((-)-RZ-2994) is an inactive(-) enantiomer of SHIN1. More details

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Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
(-)-SHIN1, Inhibitor
Full Product Name
(-)-SHIN1
Product Gene Name
(-)-SHIN1, inhibitor
Product Synonym Names
(-)-RZ-2994
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
400.47
Solubility
DMSO: 100mg/mL (249.71mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C24H24N4O2
SMILES
OCC1=CC(C2=CC=CC=C2)=CC([C@]3(C(C(C)=NN4)=C4OC(N)=C3C#N)C(C)C)=C1
Target & IC50
Others

Structure of (-)-SHIN1, inhibitor

(-)-SHIN1 Inhibitor – Cat# MBS5753905

Product References and Citations for (-)-SHIN1, inhibitor

Ducker GS, et al. Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma. Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):11404-11409.

Other Notes

Small volumes of (-)-SHIN1, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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