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Sigma-1 receptor antagonist 1 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753914

Sigma-1 receptor antagonist 1 is a potent and selective antagonist of sigma-1 receptor (sigma1R) with Ki of 1.06nM, has antineuropathic pain activity. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Sigma-1 receptor antagonist 1, Inhibitor
Full Product Name
Sigma-1 receptor antagonist 1
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
380.31
Solubility
DMSO: 6.25mg/mL (16.43mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C19H23Cl2N3O
SMILES
CC1=NC(C2=CC=C(Cl)C=C2)=NC(OCCCN3CCCCC3)=C1Cl
CAS Number
1639220-19-1
Target & IC50
sigma1R: ic50 1.06nM (ki)

Structure of Sigma-1 receptor antagonist 1, inhibitor

Sigma-1 receptor antagonist 1 Inhibitor – Cat# MBS5753914

Product References and Citations for Sigma-1 receptor antagonist 1, inhibitor

Lan Y, et al. Synthesis and biological evaluation of novel sigma-1 receptor antagonists based on pyrimidine scaffold as agents for treating neuropathic pain. J Med Chem. 2014 Dec 26;57(24):10404-23.

Other Notes

Small volumes of Sigma-1 receptor antagonist 1, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Sigma-1 receptor antagonist 1 purchase

MBS5753914 is an inhibitor targeting Sigma-1 receptor antagonist 1.
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