SMAP-2 Inhibitor

Name: SMAP-2 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5753929
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753929

SMAP-2 is an orally bioavailable activator of phosphatase 2A (PP2A) which binds to the PP2A Aalpha scaffold subunit to drive conformational changes in PP2A. It inhibits the growth of KRAS-mutant lung cancers. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SMAP-2, Inhibitor

Full Product Name

SMAP-2

Product Gene Name

SMAP-2, inhibitor

Product Synonym Names

DT-1154

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

532.57

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C27H27F3N2O4S

SMILES

O=S(C1=CC=C(OC(F)(F)F)C=C1)(N[C@@H]2[C@@H](O)[C@H](N3C4=CC=CC=C4CCC5=CC=CC=C53)CCC2)=O

CAS Number

1809068-70-9

Target & IC50

PP2A

Product Categories/Family for SMAP-2, inhibitor

Phosphatase; Others

Product References and Citations for SMAP-2, inhibitor

Sangodkar J, et al. Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth. J Clin Invest. 2017 Jun 1;127(6):2081-2090.

Other Notes

Small volumes of SMAP-2, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SMAP-2 purchase

MBS5753929 is an inhibitor targeting SMAP-2.