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Squalamine lactate Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753965

Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Squalamine lactate, Inhibitor
Full Product Name
Squalamine lactate
Product Synonym Names
MSI-1256F
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
718.04
Solubility
DMSO: 36.66mg/mL (51.06mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C37H71N3O8S
SMILES
NCCCCNCCCN[C@H]1CC[C@@]2(C)[C@](C[C@@H](O)[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CC[C@@H](OS(=O)(O)=O)C(C)C)([H])C1.C[C@@H](C(O)=O)O
CAS Number
320725-47-1
Target & IC50
Others
In Vitro
When administered intravitreally and therefore requires intravenous dosing, Squalamine is ineffective. However, systemic dosing has yielded promising results in rats as well as humans[2].

Structure of Squalamine lactate, inhibitor

Squalamine lactate Inhibitor – Cat# MBS5753965

Product References and Citations for Squalamine lactate, inhibitor

Hussain RM, et al. Emerging vascular endothelial growth factor antagonists to treat neovascular age-related macular degeneration. Expert Opin Emerg Drugs. 2017 Sep;22(3):235-246.
Hussain RM, et al. Emerging vascular endothelial growth factor antagonists to treat neovascular age-related macular degeneration. Expert Opin Emerg Drugs. 2017 Sep;22(3):235-246.
Emerson MV, et al. Current and emerging therapies for the treatment,of age-related macular degeneration. Clin Ophthalmol. 2008 Jun;2(2):377-88.
Emerson MV, et al. Current and emerging therapies for the treatment,of age-related macular degeneration. Clin Ophthalmol. 2008 Jun;2(2):377-88.

Other Notes

Small volumes of Squalamine lactate, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Squalamine lactate purchase

MBS5753965 is an inhibitor targeting Squalamine lactate.
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