T16Ainh-A01 Inhibitor

Name: T16Ainh-A01 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5753994
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753994

T16Ainh-A01 is a potent inhibitor of TMEM16A Chloride channel, inhibiting TMEM16A-mediated chloride currents (IC50 of 1uM), and functions as a calcium-activated chloride channel (CaCC). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

T16Ainh-A01, Inhibitor

Full Product Name

T16Ainh-A01

Product Gene Name

T16Ainh-A01, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

416.52

Solubility

DMF: 10mg/mL (24.01mM)
DMSO: 4mg/mL (9.6mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C19H20N4O3S2

SMILES

CCc1c(C)nc(SCC(=O)Nc2nc(cs2)-c2ccc(OC)cc2)[nH]c1=O

CAS Number

552309-42-9

Target & IC50

TMEM16A

Product Categories/Family for T16Ainh-A01, inhibitor

Membrane transporter/Ion channel

Product References and Citations for T16Ainh-A01, inhibitor

Fedigan S, et al. Effects of new-generation TMEM16A inhibitors on calcium-activated chloride currents in rabbit urethral interstitial cells of Cajal. Pflugers Arch. 2017 Nov;469(11):1443-1455.
Fedigan S, et al. Effects of new-generation TMEM16A inhibitors on calcium-activated chloride currents in rabbit urethral interstitial cells of Cajal. Pflugers Arch. 2017 Nov;469(11):1443-1455.
Namkung W, et al. TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells. J Biol Chem. 2011 Jan 21;286(3):2365-74.
Namkung W, et al. TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells. J Biol Chem. 2011 Jan 21;286(3):2365-74.

Other Notes

Small volumes of T16Ainh-A01, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for T16Ainh-A01 purchase

MBS5753994 is an inhibitor targeting T16Ainh-A01.