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UPF-648 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754082

UPF-648 is a potent kynurenine 3-monooxygenase inhibitor. It also shows highly active at 1uM (81 +/- 10% KMO inhibition). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
UPF-648, Inhibitor
Full Product Name
UPF-648
Product Gene Name
UPF-648, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
259.09
Solubility
Ethanol: 50mg/mL (192.98mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C11H8Cl2O3
SMILES
O=C([C@@H]1[C@@H](C(C2=CC=C(Cl)C(Cl)=C2)=O)C1)O
CAS Number
213400-34-1
Target & IC50
Others

Structure of UPF-648, inhibitor

UPF-648 Inhibitor – Cat# MBS5754082

Product References and Citations for UPF-648, inhibitor

Amori L, et al. On the relationship between the two branches of the kynurenine pathway in the rat brain in vivo. J Neurochem. 2009 Apr;109(2):316-25.
Ceresoli-Borroni G, et al. Perinatal kynurenine 3-hydroxylase inhibition in rodents: pathophysiological implications. J Neurosci Res. 2007 Mar;85(4):845-54.
Amaral M, et al. Structural basis of kynurenine 3-monooxygenase inhibition. Nature. 2013 Apr 18;496(7445):382-5.

Other Notes

Small volumes of UPF-648, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for UPF-648 purchase

MBS5754082 is an inhibitor targeting UPF-648.
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