WAY-213613 Inhibitor

Name: WAY-213613 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5754127
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754127

WAY-213613 is a potent and selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 (IC50: 85nM EAAT2). It displays 59- and 44-fold selectivity over EAAT1 and EAAT3 (IC50s: 5 and 3.8 uM, respectively). WAY-213613 shows no activity at ionotropic and… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

WAY-213613, Inhibitor

Full Product Name

WAY-213613

Product Gene Name

WAY-213613, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

415.19

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C16H13BrF2N2O4

SMILES

BrC(C=C(F)C(F)=C1)=C1OC2=CC=C(NC(C[C@H](N)C(O)=O)=O)C=C2

CAS Number

868359-05-1

Target & IC50

Human EAAT2: ic50 85nM
Human EAAT3: ic50 3.8uM
Human EAAT1: ic50 5uM

Product Categories/Family for WAY-213613, inhibitor

Metabolism; transporter

Product References and Citations for WAY-213613, inhibitor

Simmons DA, et al. A small molecule p75NTR ligand, LM11A-31, reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression. PLoS One. 2014 Aug 25;9(8):e102136.

Other Notes

Small volumes of WAY-213613, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WAY-213613 purchase

MBS5754127 is an inhibitor targeting WAY-213613.