YQ128 Inhibitor

Name: YQ128 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5754143
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754143

YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30uM), with anti-inflammatory activity. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

YQ128, Inhibitor

Full Product Name

YQ128

Product Gene Name

YQ128, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

545.11

Solubility

DMSO: 250mg/mL (458.62mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C27H29ClN2O4S2

SMILES

O=S(C1=CC=C(CCN(CC2=C(C=CC(Cl)=C2)OCCC)C(CC3=CSC=C3)=O)C=C1)(NCC#C)=O

Target & IC50

NLRP3: ic50 0.30uM
IL-1beta

Product Categories/Family for YQ128, inhibitor

Immunology/Inflammation; NF-kappaB

Product References and Citations for YQ128, inhibitor

Jiang Y, et al. Discovery of Second-Generation NLRP3 Inflammasome Inhibitors: Design, Synthesis, and Biological Characterization. J Med Chem. 2019 Oct 31.

Other Notes

Small volumes of YQ128, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for YQ128 purchase

MBS5754143 is an inhibitor targeting YQ128.