Zinc Protoporphyrin Inhibitor

Name: Zinc Protoporphyrin Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5754158
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754158

Zinc Protoporphyrin is an orally active and competitive inhibitor of heme oxygenase-1 (HO-1) and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2, and has anti-cancer activity. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Zinc Protoporphyrin, Inhibitor

Full Product Name

Zinc Protoporphyrin

Product Synonym Names

Zn(II)-protoporphyrin IX; ZnPP; Zinc Protoporphyrin-9

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

626.02

Solubility

DMSO: 50mg/mL (79.87mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C34H32N4O4Zn

SMILES

OC(CCC1=C(C=C2[N]3=C4C(C)=C2CCC(O)=O)[N-]([Zn+2]35[N]6=C7C=C(C(C=C)=C8C)[N-]5C8=C4)C(C=C6C(C=C)=C7C)=C1C)=O

CAS Number

15442-64-5

Target & IC50

Human Endogenous Metabolite

In Vitro

Zinc Protoporphyrin exhibits dose-dependent antitumor effects manifested by the retardation of tumor growth[3].

Product Categories/Family for Zinc Protoporphyrin, inhibitor

Chromatin/Epigenetic; Epigenetic Reader Domain; Metabolic Enzyme/Protease

Product References and Citations for Zinc Protoporphyrin, inhibitor

Park C, et al. Protective Effect of Phloroglucinol on Oxidative Stress-Induced DNA Damage and Apoptosisthrough Activation of the Nrf2/HO-1 Signaling Pathway in HaCaT Human Keratinocytes. Mar Drugs. 2019 Apr 13;17(4).
Park C, et al. Protective Effect of Phloroglucinol on Oxidative Stress-Induced DNA Damage and Apoptosisthrough Activation of the Nrf2/HO-1 Signaling Pathway in HaCaT Human Keratinocytes. Mar Drugs. 2019 Apr 13;17(4).
Mwangi MN, et al. Diagnostic utility of zinc protoporphyrin to detect iron deficiency in Kenyan pregnant women. BMC Med. 2014 Nov 26;12:229.
Mwangi MN, et al. Diagnostic utility of zinc protoporphyrin to detect iron deficiency in Kenyan pregnant women. BMC Med. 2014 Nov 26;12:229.
Nowis D, et al. Zinc protoporphyrin IX, a heme oxygenase-1 inhibitor, demonstrates potent antitumor effects but is unable to potentiate antitumor effects of chemotherapeutics in mice. BMC Cancer. 2008 Jul 11;8:197.
Nowis D, et al. Zinc protoporphyrin IX, a heme oxygenase-1 inhibitor, demonstrates potent antitumor effects but is unable to potentiate antitumor effects of chemotherapeutics in mice. BMC Cancer. 2008 Jul 11;8:197.

Other Notes

Small volumes of Zinc Protoporphyrin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Zinc Protoporphyrin purchase

MBS5754158 is an inhibitor targeting Zinc Protoporphyrin.