beta-Apo-13-carotenone Inhibitor

beta-Apo-13-carotenone is a naturally occurring beta-apocarotenoid, and is a RXRalpha antagonist.

Eroglu A, et al. The eccentric cleavage product of beta-carotene, beta-apo-13-carotenone, functions as an antagonist of RXRalpha. Arch Biochem Biophys. 2010 Dec 1;504(1):11-6.
Eroglu A, et al. The eccentric cleavage product of beta-carotene, beta-apo-13-carotenone, functions as an antagonist of RXRalpha. Arch Biochem Biophys. 2010 Dec 1;504(1):11-6.
Sun J, et al. beta-Apo-13-carotenone regulates retinoid X receptor transcriptional activity through tetramerization of the receptor. J Biol Chem. 2014 Nov 28;289(48):33118-24.
Sun J, et al. beta-Apo-13-carotenone regulates retinoid X receptor transcriptional activity through tetramerization of the receptor. J Biol Chem. 2014 Nov 28;289(48):33118-24.
Wang CX, et al. Actions of beta-apo-carotenoids in differentiating cells: differential effects in P19 cells and 3T3-L1 adipocytes. Arch Biochem Biophys. 2015 Apr 15;572:2-10.
Wang CX, et al. Actions of beta-apo-carotenoids in differentiating cells: differential effects in P19 cells and 3T3-L1 adipocytes. Arch Biochem Biophys. 2015 Apr 15;572:2-10.

Small volumes of beta-Apo-13-carotenone, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5754182 is an inhibitor targeting beta-Apo-13-carotenone.