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alphavbeta1 integrin-IN-1 TFA Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754219

alphavbeta1 integrin-IN-1 TFA is an effective and selective alphavbeta1 integrin inhibitor (IC50: 0.63nM). More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
alphavbeta1 integrin-IN-1 TFA, Inhibitor
Full Product Name
alphavbeta1 integrin-IN-1 TFA
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
672.67
Solubility
DMSO: 250mg/mL (371.65mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C28H35F3N6O8S
SMILES
O=C(O)[C@H](CC1=CC=C(NC(CCCCNC(N)=N)=O)C=C1)NC([C@H]2N(S(=O)(C3=CC=CC=C3)=O)CCC2)=O.OC(C(F)(F)F)=O
Target & IC50
alphavbeta1 integrin: ic50 0.63nM

Product References and Citations for alphavbeta1 integrin-IN-1 TFA, inhibitor

1. Reed NI, et al. Exploring N-Arylsulfonyl-l-proline Scaffold as a Platform for Potent and Selective alphavbeta1 Integrin Inhibitors. ACS Med Chem Lett. 2016 Aug 30;7(10):902-907.

Other Notes

Small volumes of alphavbeta1 integrin-IN-1 TFA, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for alphavbeta1 integrin-IN-1 TFA purchase

MBS5754219 is an inhibitor targeting alphavbeta1 integrin-IN-1 TFA.
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