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beta-Elemene Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754220

beta-Elemene is a natural product isolated from Curcuma wenyujin, with an antitumor activity and induce cell apoptosis. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
beta-Elemene, Inhibitor
Full Product Name
beta-Elemene
Product Synonym Names
(-)-beta-Elemene; Levo-beta-elemene
Form/Format
Solid. Powder
Purity/Purification
99.35%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
204.35
Solubility
DMSO: 50mg/mL (244.68mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C15H24
SMILES
CC([C@H]1[C@@](C)(CC[C@@H](C(C)=C)C1)C=C)=C
CAS Number
515-13-9
Target & IC50
Others
Cell Research
Cell viability assay was used to assess the resistance of SGC7901/ADR cells and the cytotoxic effects of beta-Elemene. Wound healing, transwell assay and lung metastatic mice model were used to the anti-metastasis effects of beta-Elemene. MicroRNA microarray analysis was used to explore potential regulated miRNAs. Luciferase reporter assay was used to identify the direct target. HumanmMP antibody array, western blot, immunoprecipitation, qRT-PCR analyses and immunohistochemistry were conducted to investigate the underlying anti-metastasis mechanism of beta-Elemene[3]. Cell lines:

Product References and Citations for beta-Elemene, inhibitor

Ross, S. A., and ElSohly, M. A. The volatile oil composition of fresh and air-dried buds of Cannabis sativa. J. Nat. Prod. 59(1), 49-51 (1996).
Ross, S. A., and ElSohly, M. A. The volatile oil composition of fresh and air-dried buds of Cannabis sativa. J. Nat. Prod. 59(1), 49-51 (1996).
Gan D, et al. beta-elemene enhances cisplatin-induced apoptosis in bladder cancer cells through the ROS-AMPK signaling pathway.Oncol Lett. 2020 Jan;19(1):291-300.
Gan D, et al. beta-elemene enhances cisplatin-induced apoptosis in bladder cancer cells through the ROS-AMPK signaling pathway.Oncol Lett. 2020 Jan;19(1):291-300.

Other Notes

Small volumes of beta-Elemene, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for beta-Elemene purchase

MBS5754220 is an inhibitor targeting beta-Elemene.
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