2'-O-Methyladenosine Inhibitor

2'-O-Methyladenosine, a methylated adenine residue is found in the urine of normals and adenosine deaminase deficient patients. It shows unique hypotensive activities.

Hirschhorn R, et al. Increased excretion of modified adenine nucleosides by children with adenosine deaminase deficiency. Pediatr Res. 1982 May;16(5):362-9.
Hirschhorn R, et al. Increased excretion of modified adenine nucleosides by children with adenosine deaminase deficiency. Pediatr Res. 1982 May;16(5):362-9.
Yamada T, et al. Naturally occurring 2'-O-methylpurine nucleosides with hypotensive properties. Cell Mol Life Sci. 1998 Feb;54(2):125-8.
Yamada T, et al. Naturally occurring 2'-O-methylpurine nucleosides with hypotensive properties. Cell Mol Life Sci. 1998 Feb;54(2):125-8.

Small volumes of 2'-O-Methyladenosine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5754222 is an inhibitor targeting 2'-O-Methyladenosine.