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6-Aminochrysene Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754235

6-Aminochrysene (6-Aminochrysene) is used as a chemotherapeutic agent in the treatment,of myeloid leukemia, splenomegaly, and breast cancer. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
6-Aminochrysene, Inhibitor
Full Product Name
6-Aminochrysene
Product Synonym Names
6-Chrysenamine
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
243.3
Solubility
DMSO: 62.5mg/mL (256.88mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C18H13N
SMILES
NC1=C2C=CC=CC2=C3C(C4=CC=CC=C4C=C3)=C1
CAS Number
2642-98-0
Target & IC50
Others
In Vitro
6-Aminochrysene is an inhibitor of the growth of several solid experimental tumors in vivo and has a cancerostatic effect on human breast cancer [1]. Long term topical skin application of 6-Aminochrysene to mice induces the development of benign skin tumors after 3 months and of skin malignancies after 7 months. Female mice respond earlier than males. The induction of skin tumors is more rapid when 6-Aminochrysene is applied ventrally instead of dorsally. Urinary excretion is about twice as high after skin application than after oral administration [2].

Product References and Citations for 6-Aminochrysene, inhibitor

Russo R, et al. Effects of 6-aminochrysene on liver microsomal enzyme activity. Xenobiotica. 1976 Apr;6(4):201-5.
Russo R, et al. Effects of 6-aminochrysene on liver microsomal enzyme activity. Xenobiotica. 1976 Apr;6(4):201-5.
Lambelin G, et al. Carcinogenicity of 6-aminochrysene in mice. Eur J Cancer. 1975 May;11(5):327-34.
Lambelin G, et al. Carcinogenicity of 6-aminochrysene in mice. Eur J Cancer. 1975 May;11(5):327-34.

Other Notes

Small volumes of 6-Aminochrysene, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 6-Aminochrysene purchase

MBS5754235 is an inhibitor targeting 6-Aminochrysene.
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