Acetoacetic acid sodium salt Inhibitor

Solid. Powder

98.00%

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

124.07

H2O: 50mg/mL (403.00mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

C4H5NaO3

CC(CC(O[Na])=O)=O

623-58-5

Others

Acetoacetic acid sodium salt induces oxidative stress to inhibit the assembly of very-low-density lipoprotein in bovine hepatocytes. Acetoacetic acid (0.6, 2.4, 4.8mM) increases malondialdehyde (MDA) content in high-dose group (GH) group, decreases mRNA expression of Mn-SOD, Cu/Zn SOD, and glutathione peroxidase (GSH-Px) in all groups, lowers catalase (CAT) mRNA expression in the medial-dose group (GM), and GH groups. In addition, Acetoacetic acid down-regulates the mRNA expression of apolipoprotein B100 (ApoB100), apolipoprotein E (ApoE), and low-density lipoprotein receptor (LDLR). Thus, VLDL assembly is decreased and triglyceride (TG) accumulation is increased in these bovine hepatocytes.