CDDO-dhTFEA Inhibitor

Name: CDDO-dhTFEA Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5754262
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754262

CDDO-dhTFEA (RTA dh404), a synthetic oleanane triterpenoid compound, potently activates Nrf2 and inhibits NF-kappaB. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CDDO-dhTFEA, Inhibitor

Full Product Name

CDDO-dhTFEA

Product Gene Name

CDDO-dhTFEA, inhibitor

Product Synonym Names

RTA dh404

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

574.72

Solubility

DMSO: 260mg/mL (452.39mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C33H45F3N2O3

SMILES

CC(C)([C@](CC[C@@]([C@@]1(CC[C@]2(CCC(C)(C[C@]2([C@]13[H])[H])C)C(NCC(F)(F)F)=O)C)4C)5[H])C(C(C#N)=C[C@]5(C)[C@@]4([H])CC3=O)=O

CAS Number

1191265-33-4

Target & IC50

Nrf2
NF-kappaB

Product Categories/Family for CDDO-dhTFEA, inhibitor

Immunology/Inflammation; NF-kappab

Product References and Citations for CDDO-dhTFEA, inhibitor

Aminzadeh MA, et al. The synthetic triterpenoid RTA dh404 (CDDO-dhTFEA) restores endothelial function impaired by reduced Nrf2 activity in chronic kidney disease. Redox Biol. 2013 Oct 31;1:527-31.
Aminzadeh MA, et al. The synthetic triterpenoid RTA dh404 (CDDO-dhTFEA) restores endothelial function impaired by reduced Nrf2 activity in chronic kidney disease. Redox Biol. 2013 Oct 31;1:527-31.
Aminzadeh MA, et al. The synthetic triterpenoid RTA dh404 (CDDO-dhTFEA) restores Nrf2 activity and attenuates oxidative stress, inflammation, and fibrosis in rats with chronic kidney disease. Xenobiotica. 2014 Jun;44(6):570-8.
Aminzadeh MA, et al. The synthetic triterpenoid RTA dh404 (CDDO-dhTFEA) restores Nrf2 activity and attenuates oxidative stress, inflammation, and fibrosis in rats with chronic kidney disease. Xenobiotica. 2014 Jun;44(6):570-8.

Other Notes

Small volumes of CDDO-dhTFEA, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDDO-dhTFEA purchase

MBS5754262 is an inhibitor targeting CDDO-dhTFEA.