CP-10 Inhibitor

Name: CP-10 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5754274
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754274

CP-10 is a PROTAC with highly selective and remarkable CDK6 degradation (DC50: 2.1nM). It inhibits the proliferation of several hematopoietic cancer cells including multiple myeloma and can degrade mutated and overexpressed CDK6. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CP-10, Inhibitor

Full Product Name

CP-10

Product Gene Name

CP-10, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

871.94

Solubility

DMSO: 200mg/mL (229.37mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C44H49N13O7

SMILES

CC(C(C1=O)=C(C)C2=CN=C(NC3=CC=C(N4CCN(CC5=CN(CCOCCNC6=CC=CC(C(N7C8CCC(NC8=O)=O)=O)=C6C7=O)N=N5)CC4)C=N3)N=C2N1C9CCCC9)=O

CAS Number

2366268-80-4

Target & IC50

CDK6: ic50 2.1nM (Dc50)
Cereblon

Product Categories/Family for CP-10, inhibitor

Cell Cycle/Checkpoint; CDK

Product References and Citations for CP-10, inhibitor

Su S, et al. Potent and Preferential Degradation of CDK6 via Proteolysis Targeting Chimera Degraders. J Med Chem. 2019 Aug 2.

Other Notes

Small volumes of CP-10, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CP-10 purchase

MBS5754274 is an inhibitor targeting CP-10.