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Homo-cereblon degrader 1 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754320

Homo-PROTAC cereblon degrader 1 is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Homo-cereblon degrader 1, Inhibitor
Full Product Name
Homo-PROTAC cereblon degrader 1
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
660.63
Solubility
DMSO: 200mg/mL (302.74mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C32H32N6O10
SMILES
O=C1N(C2CCC(=O)NC2=O)C(=O)c2c1cccc2NCCOCCOCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
CAS Number
2244520-98-5
Target & IC50
Cereblon

Structure of Homo-cereblon degrader 1, inhibitor

Homo-cereblon degrader 1 Inhibitor – Cat# MBS5754320

Product References and Citations for Homo-cereblon degrader 1, inhibitor

Steinebach C, et al. Homo-PROTACs for the Chemical Knockdown of Cereblon. ACS Chem Biol. 2018 Sep 21;13(9):2771-2782.
Steinebach C, et al. Homo-PROTACs for the Chemical Knockdown of Cereblon. ACS Chem Biol. 2018 Sep 21;13(9):2771-2782.

Other Notes

Small volumes of Homo-cereblon degrader 1, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Homo-cereblon degrader 1 purchase

MBS5754320 is an inhibitor targeting Homo-cereblon degrader 1. Also known as Homo-PROTAC cereblon degrader 1.
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