7alpha,25-Dihydroxycholesterol Inhibitor

Name: 7alpha,25-Dihydroxycholesterol Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5754447
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754447

7alpha, 25-dihydroxycholesterol (7alpha,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7alpha, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic… More details

Please Inquire

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

7alpha,25-Dihydroxycholesterol, Inhibitor

Full Product Name

7alpha,25-Dihydroxycholesterol

Product Synonym Names

7alpha,25-OHC

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

418.65

Solubility

DMSO: 1mg/mL (2.39mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C27H46O3

SMILES

[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)(C)O

CAS Number

64907-22-8

Target & IC50

Human Endogenous Metabolite
GPR183

Product Categories/Family for 7alpha,25-Dihydroxycholesterol, inhibitor

Metabolic Enzyme/Protease; GPCR/G Protein

Product References and Citations for 7alpha,25-Dihydroxycholesterol, inhibitor

Liu C, et al. Oxysterols direct B-cell migration through EBI2. Nature. 2011 Jul 27;475(7357):519-23.
Liu C, et al. Oxysterols direct B-cell migration through EBI2. Nature. 2011 Jul 27;475(7357):519-23.
Hannedouche S, et al. Oxysterols direct immune cell migration via EBINature. 2011 Jul 27;475(7357):524-7.
Hannedouche S, et al. Oxysterols direct immune cell migration via EBI2. Nature. 2011 Jul 27;475(7357):524-7.

Other Notes

Small volumes of 7alpha,25-Dihydroxycholesterol, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 7alpha,25-Dihydroxycholesterol purchase

MBS5754447 is an inhibitor targeting 7alpha,25-Dihydroxycholesterol.