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8-Bromo-cGMP sodium Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754448

8-Bromo-cGMP sodium, a membrane-permeable analogue of cGMP, is a PKG (protein kinase G) activator. 8-Bromo-cGMP sodium has antinociceptive effects[2]. 8-Bromo-cGMP sodium significantly inhibits Ca2+ macroscopic currents and impairs insulin release stimulated… More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
8-Bromo-cGMP sodium, Inhibitor
Full Product Name
8-Bromo-cGMP sodium
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
446.08
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C10H10BrN5NaO7P
SMILES
O=C1C2=C(N([C@H]3[C@H](O)[C@@](OP(OC4)(O[Na])=O)([H])[C@]4([H])O3)C(Br)=N2)NC(N)=N1
CAS Number
51116-01-9
Target & IC50
PKG
Ca2+

Product References and Citations for 8-Bromo-cGMP sodium, inhibitor

Sarkar O, et al. Nitric oxide attenuates overexpression of Gialpha proteins in vascular smooth muscle cells from SHR: Role of ROS and ROS-mediated signaling. PLoS One. 2017 Jul 10;12(7):e0179301.
Sarkar O, et al. Nitric oxide attenuates overexpression of Gialpha proteins in vascular smooth muscle cells from SHR: Role of ROS and ROS-mediated signaling. PLoS One. 2017 Jul 10;12(7):e0179301.
Tegeder I, et al. Dual effects of spinally delivered 8-bromo-cyclic guanosine mono-phosphate (8-bromo-cGMP) in formalin-induced nociception in rats. Neurosci Lett. 2002 Oct 31;332(2):146-50.
Tegeder I, et al. Dual effects of spinally delivered 8-bromo-cyclic guanosine mono-phosphate (8-bromo-cGMP) in formalin-induced nociception in rats. Neurosci Lett. 2002 Oct 31;332(2):146-50.

Other Notes

Small volumes of 8-Bromo-cGMP sodium, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 8-Bromo-cGMP sodium purchase

MBS5754448 is an inhibitor targeting 8-Bromo-cGMP sodium.
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