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A-802715 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754457

A802715 is a methylxanthine derivative and it has a TD50 (toxic dose of 50%) of 0.9-1.1 mM. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
A-802715, Inhibitor
Full Product Name
A-802715
Product Gene Name
A-802715, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
322.4
Solubility
DMSO: 190mg/mL (589.33mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C16H26N4O3
SMILES
O=C(N1CCCCC(C)(O)C)N(C)C2=C(N(CCC)C=N2)C1=O
CAS Number
107767-58-8
Target & IC50
Others
In Vitro
The toxicity of the methylxanthine derivative A802715 is determined against the two human melanoma lines, Be11 and MeWo, and against the two human squamous cell carcinoma lines, 4197 and 4451, by vital dye staining assay. In p53 wt cells BrdU incorporations show that the irradiation-induced suppression of S-phase entry is strongly enhanced by A802715. A802715 prolongs the G2/M block or remain ineffective depending on the p53 status of the cell line[1], and it has a TD50 of 0.9-1.1mM and is the most toxic.

Structure of A-802715, inhibitor

A-802715 Inhibitor – Cat# MBS5754457

Product References and Citations for A-802715, inhibitor

Bohm L, et al. Influence of pentoxifylline, A-802710, propentofylline and A-802715 (Hoechst) on the expression of cell cycle blocks and S-phase content after irradiation damage. Biochim Biophys Acta. 2000 Dec 11;1499(1-2):1-10.
Bohm L, et al. Influence of pentoxifylline, A-802710, propentofylline and A-802715 (Hoechst) on the expression of cell cycle blocks and S-phase content after irradiation damage. Biochim Biophys Acta. 2000 Dec 11;1499(1-2):1-10.

Other Notes

Small volumes of A-802715, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for A-802715 purchase

MBS5754457 is an inhibitor targeting A-802715.
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