Acetamiprid Inhibitor

Name: Acetamiprid Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5754470
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754470

Acetamiprid is a nicotinic acetylcholine receptor (nAChR) agonist. Acetamiprid is a neonicotinoid insecticide used worldwide. It is shown to be associated with neuromuscular and reproductive disorders. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Acetamiprid, Inhibitor

Full Product Name

Acetamiprid

Form/Format

Solid. Powder

Purity/Purification

99.78%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

222.67

Solubility

DMSO: 97mg/mL (435.62mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C10H11ClN4

SMILES

CN(Cc1ccc(Cl)nc1)C(C)=NC#N

CAS Number

135410-20-7

Target & IC50

nAChR

In Vitro

Acetamiprid decreases in body weight and mildly affected spermatogenesis [1]. Acetamiprid disrupts subsequent testosterone biosynthesis by decreasing the rate of conversion of cholesterol to testosterone and by preventing cholesterol from entering the mitochondria within the Leydig cells. These effects caused reproductive damage to the rats[2]. Acetamiprid decreases the expression of testosterone-metabolism genes, nAChR subunit genes, and proliferation-associated genes in mice[1].

Product Categories/Family for Acetamiprid, inhibitor

Neuroscience; AChR

Product References and Citations for Acetamiprid, inhibitor

Terayama H, et al. Effect of acetamiprid on the immature murine testes. Int J Environ Health Res. 2018 Dec;28(6):683-696.
Terayama H, et al. Effect of acetamiprid on the immature murine testes. Int J Environ Health Res. 2018 Dec;28(6):683-696.
Kong D, et al. Acetamiprid inhibits testosterone synthesis by affecting the mitochondrial function and cytoplasmic adenosine triphosphate production in rat Leydig cells. Biol Reprod. 2017 Jan 1;96(1):254-265.
Kong D, et al. Acetamiprid inhibits testosterone synthesis by affecting the mitochondrial function and cytoplasmic adenosine triphosphate production in rat Leydig cells. Biol Reprod. 2017 Jan 1;96(1):254-265.

Other Notes

Small volumes of Acetamiprid, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Acetamiprid purchase

MBS5754470 is an inhibitor targeting Acetamiprid.