AM-4668 Inhibitor

Name: AM-4668 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5754504
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754504

AM-4668 is a type 2 diabetes GPR40 agonist. For GPR40, in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), the EC50s are 3.6nM and 36nM, respectively. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AM-4668, Inhibitor

Full Product Name

AM-4668

Product Gene Name

AM-4668, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

488.48

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C24H19F3N2O4S

SMILES

OC(C[C@H](C1=NOC=C1)C(C=C2)=CC=C2OCC(S3)=C(C)N=C3C4=CC=C(C(F)(F)F)C=C4)=O

CAS Number

1011531-27-3

Target & IC50

GPR40: ic50 3.6nM (EC50)
GPR40, in CHO cells: ic50 36nM (EC50)

Product Categories/Family for AM-4668, inhibitor

Endocrinology/Hormones; GPR; GPCR/G Protein

Product References and Citations for AM-4668, inhibitor

Liu JJ, et al. Optimization of GPR40 Agonists for Type 2 Diabetes. ACS Med Chem Lett. 2014 Feb 6;5(5):517-21.
Liu JJ, et al. Optimization of GPR40 Agonists for Type 2 Diabetes. ACS Med Chem Lett. 2014 Feb 6;5(5):517-21.

Other Notes

Small volumes of AM-4668, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AM-4668 purchase

MBS5754504 is an inhibitor targeting AM-4668.