Apararenone Inhibitor

Name: Apararenone Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5754522
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754522

Apararenone is a novel antagonist of non-steroidal mineralocorticoid receptor, and for the treatment,of diabetic nephropathies and non-alcoholic steatohepatitis. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Apararenone, Inhibitor

Full Product Name

Apararenone

Product Synonym Names

MT-3995

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

364.39

Solubility

DMSO: 125mg/mL (343.04mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C17H17FN2O4S

SMILES

O=C1N(C2=CC=C(F)C=C2)C3=CC=C(NS(C)(=O)=O)C=C3OC1(C)C

CAS Number

945966-46-1

Target & IC50

Mineralocorticoid receptor

In Vitro

A phase II clinical trial has been initiated among patients with non-alcoholic steatohepatitis (NASH) in Japan[1].

Product Categories/Family for Apararenone, inhibitor

Endocrinology/Hormones; Glucocorticoid Receptor

Product References and Citations for Apararenone, inhibitor

Kolkhof P, et al. 30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Mineralocorticoid receptor antagonists: 60 years of research and development. J Endocrinol. 2017 Jul;234(1):T125-T140.
Kolkhof P, et al. 30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Mineralocorticoid receptor antagonists: 60 years of research and development. J Endocrinol. 2017 Jul;234(1):T125-T140.

Other Notes

Small volumes of Apararenone, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Apararenone purchase

MBS5754522 is an inhibitor targeting Apararenone.