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Apronal Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754528

Apronal (Allylisopropylacetylurea, Apronalide) is a hypnotic and sedative drug. It has been withdrawn in several countries due to side effects. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Apronal, Inhibitor
Full Product Name
Apronal
Product Synonym Names
Allylisopropylacetylurea; Apronalide
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
184.24
Solubility
DMSO: 165mg/mL (895.57mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C9H16N2O2
SMILES
C=CCC(C(C)C)C(NC(N)=O)=O
CAS Number
528-92-7
Target & IC50
Others
In Vitro
Research shows that allylisopropylacetylurea increases the amount of porphyrins in the liver and urine of animals. And it brings about a marked green pigmentation of the liver. Lesions originated by long-term administration with allylisopropylacetylurea can be tolerated by rats and are reversible[1]. Rats recover well from long-term treatment with high doses of allylisopropylacetylurea and revert to normal values for parameters measured. Fixed drug eruption and mucocutaneous ocular syndrome are reported due to apronal[2].

Structure of Apronal, inhibitor

Apronal Inhibitor – Cat# MBS5754528

Product References and Citations for Apronal, inhibitor

Rentsch G, et al. The effect of prolonged administration of allylisopropylacetylurea to rats on cytochrome P-450 and other liver haemoproteins. Xenobiotica. 1976 Mar;6(3):151-7.
Rentsch G, et al. The effect of prolonged administration of allylisopropylacetylurea to rats on cytochrome P-450 and other liver haemoproteins. Xenobiotica. 1976 Mar;6(3):151-7.
Fujimoto Y, et al. Fixed drug eruption due to allylisopropylacetylurea. Contact Dermatitis. 1993 May;28(5):282-4.
Fujimoto Y, et al. Fixed drug eruption due to allylisopropylacetylurea. Contact Dermatitis. 1993 May;28(5):282-4.

Other Notes

Small volumes of Apronal, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Apronal purchase

MBS5754528 is an inhibitor targeting Apronal.
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