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Artemisone Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754533

Artemisone is a potent and semi-synthetic antimalarial(inhibits P. falciparum strains, IC50 :0.83nM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Artemisone, Inhibitor
Full Product Name
Artemisone
Product Synonym Names
Artemifone; BAY 44-9585
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
401.52
Solubility
DMSO: 130mg/mL (323.77mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C19H31NO6S
SMILES
C[C@H]1[C@H](N2CCS(CC2)(=O)=O)O[C@@]3([H])[C@]45[C@@]([C@H](C)CC[C@]51[H])([H])CC[C@@](O3)(C)OO4
CAS Number
255730-18-8
Target & IC50
P. falciparum: ic50 0.83nM
In Vitro
Artemisone (3, 1, 0.3 and 0.1mg/kg, s.c.) in combination with ohter antimalarials has enhanced effect against the chloroquine-resistant line P. yoelii NS[1] Artemisone is effectve at inhibiting the parasitaemia in the P. berghei NY susceptible strain, with an ED50 of 9.62mg/kg via subcutaneous route and 11.67mg/kg via oral administration[1].

Structure of Artemisone, inhibitor

Artemisone Inhibitor – Cat# MBS5754533

Product References and Citations for Artemisone, inhibitor

Vivas L, et al. Antimalarial efficacy and drug interactions of the novel semi-synthetic endoperoxide artemisone in vitro and in vivo. J Antimicrob Chemother. 2007 Apr;59(4):658-65.
Vivas L, et al. Antimalarial efficacy and drug interactions of the novel semi-synthetic endoperoxide artemisone in vitro and in vivo. J Antimicrob Chemother. 2007 Apr;59(4):658-65.

Other Notes

Small volumes of Artemisone, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Artemisone purchase

MBS5754533 is an inhibitor targeting Artemisone.
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