AZD3988 Inhibitor

Name: AZD3988 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5754561
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754561

AZD3988 is an inhibitor of diacylglycerol acyl transferase-1 (DGAT-1). For human, rat, mouse, the IC50s values are 6, 5, 11nM, respectively. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AZD3988, Inhibitor

Full Product Name

AZD3988

Product Gene Name

AZD3988, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

456.44

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C23H22F2N4O4

SMILES

O=C(NC1=CC=C(C=C1)[C@H](CC2)CC[C@@H]2CC(O)=O)C3=NN=C(NC4=CC=C(C(F)=C4)F)O3

CAS Number

892489-52-0

Target & IC50

h DGAT-1: ic50 6nM
Rat DGAT-1: ic50 5nM
Mouse DGAT-1: ic50 11nM

Product Categories/Family for AZD3988, inhibitor

Metabolism; Transferase

Product References and Citations for AZD3988, inhibitor

McCoull W, et al. Identification, optimisation and in vivo evaluation of oxadiazole DGAT-1 inhibitors for the treatment,of obesity and diabetes. Bioorg Med Chem Lett. 2012 Jun 15;22(12):3873-8.
McCoull W, et al. Identification, optimisation and in vivo evaluation of oxadiazole DGAT-1 inhibitors for the treatment,of obesity and diabetes. Bioorg Med Chem Lett. 2012 Jun 15;22(12):3873-8.

Other Notes

Small volumes of AZD3988, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AZD3988 purchase

MBS5754561 is an inhibitor targeting AZD3988.