AZD9567 Inhibitor

Name: AZD9567 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5754571
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754571

AZD9567 (compound 15) is a potent, oral active, non-steroidal and selective glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8nM. It shows excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation[1]. More details

Please Inquire

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AZD9567, Inhibitor

Full Product Name

AZD9567

Product Gene Name

AZD9567, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

494.53

Solubility

H2O: <0.1mg/mL (insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C27H28F2N4O3

SMILES

CC(F)(F)C(N[C@H]([C@H](OC1=CC2=C(N(C(C=C3)=CN(C)C3=O)N=C2)C=C1)C4=CC=CC=C4)C(C)C)=O

CAS Number

1893415-00-3

Target & IC50

Glucocorticoid receptor: ic50 3.8nM

In Vitro

AZD9567 (15mg/kg/day, Oral gavage daily for 8 days) treatment,shows excellent in vivo efficacy in a rat model of joint inflammation[1].

Product Categories/Family for AZD9567, inhibitor

Metabolism; GR

Product References and Citations for AZD9567, inhibitor

Ripa L, et al. Discovery of a Novel Oral Glucocorticoid Receptor Modulator (AZD9567) with Improved Side Effect Profile. J Med Chem. 2018 Mar 8;61(5):1785-1799.
Ripa L, et al. Discovery of a Novel Oral Glucocorticoid Receptor Modulator (AZD9567) with Improved Side Effect Profile. J Med Chem. 2018 Mar 8;61(5):1785-1799.

Other Notes

Small volumes of AZD9567, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AZD9567 purchase

MBS5754571 is an inhibitor targeting AZD9567.