AZM475271 Inhibitor

MBS5754572 is an inhibitor targeting AZM475271. AZM475271 is a potent and selective inhibitor of Src kinase(IC50 : 5nM)

Ple PA, et al. Discovery of a new class of anilinoquinazoline inhibitors with high affinity and specificity for the tyrosine kinase domain of c-Src. J Med Chem. 2004 Feb 12;47(4):871-87.
Ple PA, et al. Discovery of a new class of anilinoquinazoline inhibitors with high affinity and specificity for the tyrosine kinase domain of c-Src. J Med Chem. 2004 Feb 12;47(4):871-87.
Yezhelyev MV, et al. Inhibition of SRC tyrosine kinase as treatment, for human pancreatic cancer growing orthotopically in nude mice. Clin Cancer Res. 2004 Dec 1;10(23):8028-36.
Yezhelyev MV, et al. Inhibition of SRC tyrosine kinase as treatment, for human pancreatic cancer growing orthotopically in nude mice. Clin Cancer Res. 2004 Dec 1;10(23):8028-36.

Small volumes of AZM475271, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.