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BI8622 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754609

MBS5754609 is an inhibitor targeting BI8622. BI8622 is an ubiquitin ligase HUWE1 inhibitor (IC50: 3.1uM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BI8622, Inhibitor
Full Product Name
BI8622
Product Gene Name
BI8622, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
426.51
Solubility
DMSO: 125mg/mL (293.08mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C25H26N6O
SMILES
O=C(C1=NC=NC(N2CCC(C3=CC=CC=C3)(C#N)CC2)=C1C)NC4=CC=C(CN)C=C4
CAS Number
1875036-74-0
Target & IC50
HUWE1: ic50 3.1uM

Structure of BI8622, inhibitor

BI8622 Inhibitor – Cat# MBS5754609

Product References and Citations for BI8622, inhibitor

Peter S, et al. Tumor cell-specific inhibition of MYC function using small molecule inhibitors of the HUWE1 ubiquitin ligase. EMBO Mol Med. 2014 Dec;6(12):1525-41.
Peter S, et al. Tumor cell-specific inhibition of MYC function using small molecule inhibitors of the HUWE1 ubiquitin ligase. EMBO Mol Med. 2014 Dec;6(12):1525-41.

Other Notes

Small volumes of BI8622, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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