BMS-983970 Inhibitor

Name: BMS-983970 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5754631
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754631

BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment,of multiplecancers. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

BMS-983970, Inhibitor

Full Product Name

BMS-983970

Product Gene Name

BMS-983970, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

518.5

Solubility

DMSO: 50mg/mL (96.43mM)
H2O: <0.1mg/mL (insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C26H26F4N4O3

SMILES

O=C(N[C@@H]1C(NC2=C(F)C=CC=C2C(C3=CC=CC=C3)=N1)=O)[C@H](CCC(F)(F)F)[C@H](CC4CC4)C(N)=O

CAS Number

1584713-87-0

Target & IC50

Notch

In Vitro

BMS-983970 demonstrates anti-tumor activity in T-cell acute lymphoblastic leukemia (T-ALL) and solid tumor xenograft models[1].

Product Categories/Family for BMS-983970, inhibitor

Neuroscience; Gamma-secretase; Proteases/Proteasome; Stem Cells

Product References and Citations for BMS-983970, inhibitor

Ashvinikumar V. Gavai, et al. Abstract 1643: BMS-983970, an oral pan-Notch inhibitor for the treatment,of cancer. Cancer Res October 1, 2014 74; 1643.
Ashvinikumar V. Gavai, et al. Abstract 1643: BMS-983970, an oral pan-Notch inhibitor for the treatment,of cancer. Cancer Res October 1, 2014 74; 1643.

Other Notes

Small volumes of BMS-983970, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BMS-983970 purchase

MBS5754631 is an inhibitor targeting BMS-983970.